Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation

Post-translational modifications play a key role in tau protein aggregation and related neurodegeneration. Because hyperphosphorylation alone does not necessarily cause tau aggregation, other post-translational modifications have been recently explored. Tau acetylation promotes aggregation and inhib...

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Detalhes bibliográficos
Main Authors: Grinberg, Lea Tenenholz, Wang, Xuehua, Wang, Chao, Sohn, Peter Dongmin, Theofilas, Panos, Sidhu, Manu, Arevalo, John Benjamin, Heinsen, Helmut, Huang, Eric J., Rosen, Howard, Miller, Bruce L., Gan, Li, Seeley, William W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692283/
https://ncbi.nlm.nih.gov/pubmed/23371364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1080-2
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