Inhibition of Human Immunodeficiency Virus Type 1 Replication by RNA Interference Directed against Human Transcription Elongation Factor P-TEFb (CDK9/CyclinT1)

The human positive transcription elongation factor P-TEFb is composed of two subunits, cyclin T1 (hCycT1) and CDK9, and is involved in transcriptional regulation of cellular genes as well as human immunodeficiency virus type 1 (HIV-1) mRNA. Replication of HIV-1 requires the Tat protein, which activa...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Chiu, Ya-Lin, Cao, Hong, Jacque, Jean-Marc, Stevenson, Mario, Rana, Tariq M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2004
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369228/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14963154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.5.2517-2529.2004
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