In Silico Evaluation of an Artificial Pancreas Combining Exogenous Ultrafast-Acting Technosphere Insulin with Zone Model Predictive Control

BACKGROUND: Because of the slow pharmacokinetics of subcutaneous (SC) insulin, avoiding postprandial hyperglycemia has been a major challenge for an artificial pancreas (AP) using SC insulin without a meal announcement. METHODS: A semiautomated AP with Technosphere® Insulin (TI; MannKind Corporation...

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Main Authors: Lee, Justin J., Dassau, Eyal, Zisser, Howard, Harvey, Rebecca A., Jovanovič, Lois, Doyle, Francis J.
格式: Artigo
語言:Inglês
出版: Diabetes Technology Society 2013
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692236/
https://ncbi.nlm.nih.gov/pubmed/23439180
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