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In Silico Evaluation of an Artificial Pancreas Combining Exogenous Ultrafast-Acting Technosphere Insulin with Zone Model Predictive Control
BACKGROUND: Because of the slow pharmacokinetics of subcutaneous (SC) insulin, avoiding postprandial hyperglycemia has been a major challenge for an artificial pancreas (AP) using SC insulin without a meal announcement. METHODS: A semiautomated AP with Technosphere® Insulin (TI; MannKind Corporation...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Diabetes Technology Society
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3692236/ https://ncbi.nlm.nih.gov/pubmed/23439180 |
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