Modification to the Capsid of the Adenovirus Vector That Enhances Dendritic Cell Infection and Transgene-Specific Cellular Immune Responses

Adenovirus (Ad) gene transfer vectors can be used to transfer and express antigens and function as strong adjuvants and thus are useful platforms for the development of genetic vaccines. Based on the hypothesis that Ad vectors with enhanced infectibility of dendritic cells (DC) may be able to evoke...

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Main Authors: Worgall, Stefan, Busch, Annette, Rivara, Michael, Bonnyay, David, Leopold, Philip L., Merritt, Robert, Hackett, Neil R., Rovelink, Peter W., Bruder, Joseph T., Wickham, Thomas J., Kovesdi, Imi, Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Gene Therapy
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC369215/
https://ncbi.nlm.nih.gov/pubmed/14963160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.5.2572-2580.2004
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