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Transforming activity of DNA fragments from normal human lymphocytes results from spontaneous activation of a c-Ha-ras1 gene.

An activated human Ha-ras gene was present in a secondary NIH 3T3 transformant isolated after serial transfection of originally low-molecular-weight DNA fragments from normal human cells. This gene appeared to have acquired its transforming properties by a spontaneous mutation in codon 12 by substit...

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Hlavní autoři: Schäfer, R, Griegel, S, Schwarte, I, Geisse, S, Traub, O, Willecke, K
Médium: Artigo
Jazyk:Inglês
Vydáno: 1985
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC369193/
https://ncbi.nlm.nih.gov/pubmed/3837849
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