Blocking of α4β7 Gut-Homing Integrin during Acute Infection Leads to Decreased Plasma and Gastrointestinal Tissue Viral Loads in Simian Immunodeficiency Virus-Infected Rhesus Macaques

Intravenous administration of a novel recombinant rhesus mAb against the α4β7 gut-homing integrin (mAb) into rhesus macaques just prior to and during acute SIV infection resulted in significant decrease in plasma and gastrointestinal (GI) tissue viral load and a marked reduction in GI tissue provira...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ansari, Aftab A., Reimann, Keith A., Mayne, Ann E., Takahashi, Yoshiaki, Stephenson, Susan T., Wang, Rijian, Wang, Xinyue, Li, Jichu, Price, Andrew A., Little, Dawn M., Zaidi, Mohammad, Lyles, Robert, Villinger, Francois
التنسيق: Artigo
اللغة:Inglês
منشور في: 2010
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691699/
https://ncbi.nlm.nih.gov/pubmed/21149598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003052
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة