Blocking of α4β7 Gut-Homing Integrin during Acute Infection Leads to Decreased Plasma and Gastrointestinal Tissue Viral Loads in Simian Immunodeficiency Virus-Infected Rhesus Macaques

Intravenous administration of a novel recombinant rhesus mAb against the α4β7 gut-homing integrin (mAb) into rhesus macaques just prior to and during acute SIV infection resulted in significant decrease in plasma and gastrointestinal (GI) tissue viral load and a marked reduction in GI tissue provira...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ansari, Aftab A., Reimann, Keith A., Mayne, Ann E., Takahashi, Yoshiaki, Stephenson, Susan T., Wang, Rijian, Wang, Xinyue, Li, Jichu, Price, Andrew A., Little, Dawn M., Zaidi, Mohammad, Lyles, Robert, Villinger, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691699/
https://ncbi.nlm.nih.gov/pubmed/21149598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003052
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados