Staphylococcus aureus biofilms decrease osteoblast viability, inhibits osteogenic differentiation, and increases bone resorption in vitro

BACKGROUND: Osteomyelitis is a severe and often debilitating disease characterized by inflammatory destruction of bone. Despite treatment, chronic infection often develops which is associated with increased rates of treatment failure, delayed osseous-union, and extremity amputation. Within affected...

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Main Authors: Sanchez, Carlos J, Ward, Catherine L, Romano, Desiree R, Hurtgen, Brady J, Hardy, Sharanda K, Woodbury, Ronald L, Trevino, Alex V, Rathbone, Christopher R, Wenke, Joseph C
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691632/
https://ncbi.nlm.nih.gov/pubmed/23767824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-14-187
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