Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca(2+) in mitochondrial dynamics

Alzheimer's disease (AD) is the most common type of age-related dementia. The disease is characterized by a progressive loss of cognitive abilities, severe neurodegeneration, synaptic loss and mitochondrial dysfunction. The Wnt signaling pathway participates in the development of the central ne...

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Hlavní autoři: Silva-Alvarez, Carmen, Arrázola, Macarena S., Godoy, Juan A., Ordenes, Daniela, Inestrosa, Nibaldo C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691552/
https://ncbi.nlm.nih.gov/pubmed/23805073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00097
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