Clinical Pharmacokinetics of Buffered Propranolol Sublingual Tablet (Promptol™)—Application of a New “Physiologically Based” Model to Assess Absorption and Disposition

Sublingual administration of certain buffered propranolol may improve the rate and extent of absorption compared to oral administration. The main objectives of this study were to (1) compare the plasma propranolol concentrations (Cp-prop) following sublingual administration of a specially buffered f...

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Autores principales: Wang, Yanfeng, Wang, Zhijun, Zuo, Zhong, Tomlinson, Brian, Lee, Benjamin T. K., Bolger, Michael B., Chow, Moses S. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691420/
https://ncbi.nlm.nih.gov/pubmed/23605805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9479-1
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