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Tumorspheres but Not Adherent Cells Derived from Retinoblastoma Tumors Are of Malignant Origin

Verification that cell lines used for cancer research are derived from malignant cells in primary tumors is imperative to avoid invalidation of study results. Retinoblastoma is a childhood ocular tumor that develops from loss of functional retinoblastoma protein (pRb) as a result of genetic or epige...

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Detalhes bibliográficos
Main Authors: Bond, Wesley S., Akinfenwa, Patricia Y., Perlaky, Laszlo, Hurwitz, Mary Y., Hurwitz, Richard L., Chévez-Barrios, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691222/
https://ncbi.nlm.nih.gov/pubmed/23826078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063519
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