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Discovery of Undefined Protein Crosslinking Chemistry: A Comprehensive Methodology Utilizing (18)O-labeling and Mass Spectrometry
Characterization of protein crosslinking, particularly without prior knowledge of the chemical nature and site of crosslinking, poses a significant challenge due to their intrinsic structural complexity and the lack of a comprehensive analytical approach. Towards this end, we have developed a genera...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691076/ https://ncbi.nlm.nih.gov/pubmed/23634697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400666p |
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