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Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme

Peptidoglycan hydrolases are an effective new source of antimicrobials. A chimeric fusion protein of the Ply187 endopeptidase domain and LysK SH3b cell wall binding domain is a potent agent against Staphylococcus aureus in four functional assays.

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Bibliographische Detailangaben
Hauptverfasser: Mao, Jinzhe, Schmelcher, Mathias, Harty, William J., Foster-Frey, Juli, Donovan, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690576/
https://ncbi.nlm.nih.gov/pubmed/23413880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1574-6968.12104
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