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Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme

Peptidoglycan hydrolases are an effective new source of antimicrobials. A chimeric fusion protein of the Ply187 endopeptidase domain and LysK SH3b cell wall binding domain is a potent agent against Staphylococcus aureus in four functional assays.

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Bibliografiska uppgifter
Huvudupphovsmän: Mao, Jinzhe, Schmelcher, Mathias, Harty, William J., Foster-Frey, Juli, Donovan, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690576/
https://ncbi.nlm.nih.gov/pubmed/23413880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1574-6968.12104
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