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Immunoglobulin variable regions in molecules exhibiting characteristics of innate and adaptive immune receptors

The antigen combining sites of immunoglobulin (Ig) and T cell antigen receptors (TCRs), which are present in all jawed vertebrates, consist of a paired variable (V) domain heterodimer that exhibits varying degrees of germline- and extraordinarily high levels of somatically-derived variation. The nea...

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Bibliografiske detaljer
Main Authors: Litman, Gary W., Cannon, John P., Dishaw, Larry J., Haire, Robert N., Eason, Donna D., Yoder, Jeffrey A., Prada, Jose Hernandez, Ostrov, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690489/
https://ncbi.nlm.nih.gov/pubmed/17917037
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