Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men

Controversy surrounds the use of PSA as a biomarker for prostate cancer detection, leaving an unmet need for a novel biomarker in this setting; urinary EN2 may identify individuals with clinically relevant prostate cancer. Male BRCA1 and BRCA2 mutation carriers are at increased risk of clinically si...

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Main Authors: Killick, Emma, Morgan, Richard, Launchbury, Francesca, Bancroft, Elizabeth, Page, Elizabeth, Castro, Elena, Kote-Jarai, Zsofia, Aprikian, Armen, Blanco, Ignacio, Clowes, Virginia, Domchek, Susan, Douglas, Fiona, Eccles, Diana, Evans, D. Gareth, Harris, Marion, Kirk, Judy, Lam, Jimmy, Lindeman, Geoffrey, Mitchell, Gillian, Pachter, Nicholas, Selkirk, Christina, Tucker, Kathy, Zgajnar, Janaz, Eeles, Rosalind, Pandha, Hardev
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690389/
https://ncbi.nlm.nih.gov/pubmed/23792811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02059
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