TRPV1 and TRPA1 Antagonists Prevent the Transition of Acute to Chronic Inflammation and Pain in Chronic Pancreatitis

Visceral afferents expressing transient receptor potential (TRP) channels TRPV1 and TRPA1 are thought to be required for neurogenic inflammation and development of inflammatory hyperalgesia. Using a mouse model of chronic pancreatitis (CP) produced by repeated episodes (twice weekly) of caerulein-in...

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Hauptverfasser: Schwartz, Erica S., La, Jun-Ho, Scheff, Nicole N., Davis, Brian M., Albers, Kathryn M., Gebhart, G.F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690366/
https://ncbi.nlm.nih.gov/pubmed/23536075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1806-12.2013
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