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Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of Tuberous Sclerosis

Neural circuits are regulated by activity-dependent feedback systems that tightly control network excitability and which are thought to be crucial for proper brain development. Defects in the ability to establish and maintain network homeostasis may be central to the pathogenesis of neurodevelopment...

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Detalhes bibliográficos
Main Authors: Bateup, Helen S., Johnson, Caroline A., Denefrio, Cassandra L., Saulnier, Jessica L., Kornacker, Karl, Sabatini, Bernardo L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690324/
https://ncbi.nlm.nih.gov/pubmed/23664616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.03.017
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