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A human parvovirus, adeno-associated virus, as a eucaryotic vector: transient expression and encapsidation of the procaryotic gene for chloramphenicol acetyltransferase.

We have used the defective human parvovirus adeno-associated virus (AAV) as a novel eucaryotic vector (parvector) for the expression of a foreign gene in human cells. The recombinant, pAV2, contains the AAV genome in a pBR322-derived bacterial plasmid. When pAV2 is transfected into human cells toget...

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Main Authors: Tratschin, J D, West, M H, Sandbank, T, Carter, B J
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC369024/
https://ncbi.nlm.nih.gov/pubmed/6095038
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