Genetic Inhibition of Fibroblast Growth Factor Receptor 1 in Knee Cartilage Attenuates the Degeneration of Articular Cartilage in Adult Mice

OBJECTIVE: Fibroblast growth factor (FGF) family members are involved in the regulation of articular cartilage homeostasis. The aim of this study was to investigate the function of FGF receptor 1 (FGFR-1) in the development of osteoarthritis (OA) and its underlying mechanisms. METHODS: FGFR-1 was de...

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Bibliographic Details
Main Authors: Weng, Tujun, Yi, Lingxian, Huang, Junlan, Luo, Fengtao, Wen, Xuan, Du, Xiaolan, Chen, Qian, Deng, Chuxia, Chen, Di, Chen, Lin
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690192/
https://ncbi.nlm.nih.gov/pubmed/22833219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34645
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