Low Dose Ultraviolet B Irradiation Increases Hyaluronan Synthesis in Epidermal Keratinocytes via Sequential Induction of Hyaluronan Synthases Has1–3 Mediated by p38 and Ca(2+)/Calmodulin-dependent Protein Kinase II (CaMKII) Signaling

Hyaluronan, a major epidermal extracellular matrix component, responds strongly to different kinds of injuries. This also occurs by UV radiation, but the mechanisms involved are poorly understood. The effects of a single ultraviolet B (UVB) exposure on hyaluronan content and molecular mass, and expr...

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Main Authors: Rauhala, Leena, Hämäläinen, Lasse, Salonen, Pauliina, Bart, Geneviève, Tammi, Markku, Pasonen-Seppänen, Sanna, Tammi, Raija
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689945/
https://ncbi.nlm.nih.gov/pubmed/23645665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472530
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