Androgens Up-regulate Transcription of the Notch Inhibitor Numb in C2C12 Myoblasts via Wnt/β-Catenin Signaling to T Cell Factor Elements in the Numb Promoter

Androgen signaling via the androgen receptor is a key pathway that contributes to development, cell fate decisions, and differentiation, including that of myogenic progenitors. Androgens and synthetic steroids have well established anabolic actions on skeletal muscle. Wnt and Notch signaling pathway...

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Bibliografske podrobnosti
Main Authors: Liu, Xin-Hua, Wu, Yong, Yao, Shen, Levine, Alice C., Kirschenbaum, Alexander, Collier, Lauren, Bauman, William A., Cardozo, Christopher P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689944/
https://ncbi.nlm.nih.gov/pubmed/23649620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.478487
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