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A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation.

We have constructed mutants by using linker insertion followed by deletion in the region of cloned Rous sarcoma virus DNA coding for the N-terminal 9 kilodaltons of the src protein. Previous work implicated this region in the membrane association of the protein. The mutations had little effect on sr...

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Detalhes bibliográficos
Main Authors: Cross, F R, Garber, E A, Pellman, D, Hanafusa, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC368993/
https://ncbi.nlm.nih.gov/pubmed/6092942
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