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FEASIBILITY AND DOSE DISCOVERY ANALYSIS OF ZOLEDRONIC ACID WITH CONCURRENT CHEMOTHERAPY IN THE TREATMENT OF NEWLY DIAGNOSED METASTATIC OSTEOSARCOMA: A REPORT FROM THE CHILDEREN’S ONCOLOGY GROUP
AIM: Patients with metastatic osteosarcoma (OS) have a poor outcome with conventional therapies. Zoledronic acid (ZA) is a third-generation bisphosphonate that reduces skeletal-related events in many adult cancers, and preclinical data suggests a possible benefit in OS. This study assessed the maxim...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3689577/ https://ncbi.nlm.nih.gov/pubmed/23664013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2013.03.018 |
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