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Endogenous Somatostatin Is Critical in Regulating the Acute Effects of l-Arginine on Growth Hormone and Insulin Release in Mice

l-arginine (l-Arg) rapidly stimulates GH and insulin release in vivo. It has been hypothesized that l-Arg stimulates GH release by lowering hypothalamic somatostatin (SST) tone. l-Arg may also act directly at the pituitary to stimulate GH release. Moreover, l-Arg has a direct stimulatory effect on β...

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Autors principals: Córdoba-Chacón, Jose, Gahete, Manuel D., Pozo-Salas, Ana I., Castaño, Justo P., Kineman, Rhonda D., Luque, Raul M.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689276/
https://ncbi.nlm.nih.gov/pubmed/23696563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1136
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