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Prostaglandin E(2) Promotes UV Radiation-Induced Immune Suppression through DNA Hypermethylation

Exposure of mice to UV radiation results in suppression of the contact hypersensitivity (CHS) response. Here, we report that the UV-induced suppression of CHS is associated with increases in the levels of cyclooxygenase-2 (COX-2), prostaglandin E(2) (PGE(2)), and PGE(2) receptors in the exposed skin...

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Detalhes bibliográficos
Main Authors: Prasad, Ram, Katiyar, Santosh K
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689242/
https://ncbi.nlm.nih.gov/pubmed/23814491
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