Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation

The circadian clock orchestrates temporal patterns of physiology and behavior relative to the environmental light:dark cycle by generating and organizing transcriptional and biochemical rhythms in cells and tissues throughout the body. Circadian clock genes have been shown to regulate the physiology...

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Main Authors: Summa, Keith C., Voigt, Robin M., Forsyth, Christopher B., Shaikh, Maliha, Cavanaugh, Kate, Tang, Yueming, Vitaterna, Martha Hotz, Song, Shiwen, Turek, Fred W., Keshavarzian, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688973/
https://ncbi.nlm.nih.gov/pubmed/23825629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067102
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