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Diminished Memory T-Cell Expansion Due to Delayed Kinetics of Antigen Expression by Lentivectors

Memory CD8(+) T lymphocytes play a central role in protective immunity. In attempt to increase the frequencies of memory CD8(+) T cells, repeated immunizations with viral vectors are regularly explored. Lentivectors have emerged as a powerful vaccine modality with relatively low pre-existing and ant...

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Bibliografische gegevens
Hoofdauteurs: Furmanov, Karina, Elnekave, Mazal, Sa'eed, Abdallah, Segev, Hadas, Eli-Berchoer, Luba, Kotton, Darrell N., Bachrach, Gilad, Hovav, Avi-Hai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688922/
https://ncbi.nlm.nih.gov/pubmed/23824049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066488
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