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Diminished Memory T-Cell Expansion Due to Delayed Kinetics of Antigen Expression by Lentivectors
Memory CD8(+) T lymphocytes play a central role in protective immunity. In attempt to increase the frequencies of memory CD8(+) T cells, repeated immunizations with viral vectors are regularly explored. Lentivectors have emerged as a powerful vaccine modality with relatively low pre-existing and ant...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688922/ https://ncbi.nlm.nih.gov/pubmed/23824049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066488 |
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