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Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium

Several deleterious intra-acinar phenomena are simultaneously triggered on initiating acute pancreatitis. These culminate in acinar injury or inflammatory mediator generation in vitro and parenchymal damage in vivo. Supraphysiologic caerulein is one such initiator which simultaneously activates nume...

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Detalhes bibliográficos
Main Authors: Mishra, Vivek, Cline, Rachel, Noel, Pawan, Karlsson, Jenny, Baty, Catherine J., Orlichenko, Lidiya, Patel, Krutika, Trivedi, Ram Narayan, Husain, Sohail Z., Acharya, Chathur, Durgampudi, Chandra, Stolz, Donna B., Navina, Sarah, Singh, Vijay P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688910/
https://ncbi.nlm.nih.gov/pubmed/23824669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066471
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