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Toxoplasma gondii Proliferation Require Down-Regulation of Host Nox4 Expression via Activation of PI3 Kinase/Akt Signaling Pathway

Toxoplasma gondii results in ocular toxoplasmosis characterized by chorioretinitis with inflammation and necrosis of the neuroretina, pigment epithelium, and choroid. After invasion, T. gondii replicates in host cells before cell lysis, which releases the parasites to invade neighboring cells to rep...

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Bibliografische gegevens
Hoofdauteurs: Zhou, Wei, Quan, Juan-Hua, Lee, Young-Ha, Shin, Dae-Whan, Cha, Guang-Ho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688893/
https://ncbi.nlm.nih.gov/pubmed/23824914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066306
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