LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys

Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator that represents a promising target for the treatment of several metabolic diseases. Administration of recombinant wild type FGF21 to diabetic animals leads to a dramatic improvement in glycaemia and ameliorates other systemic measure...

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Detalhes bibliográficos
Main Authors: Adams, Andrew C., Halstead, Carolyn A., Hansen, Barbara C., Irizarry, Armando R., Martin, Jennifer A., Myers, Sharon R., Reynolds, Vincent L., Smith, Holly W., Wroblewski, Victor J., Kharitonenkov, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688819/
https://ncbi.nlm.nih.gov/pubmed/23823755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065763
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