Inhibition of FLT3 Expression by Green Tea Catechins in FLT3 Mutated-AML Cells

Acute myeloid leukemia (AML) is a heterogeneous disease characterized by a block in differentiation and uncontrolled proliferation. FLT3 is a commonly mutated gene found in AML patients. In clinical trials, the presence of a FLT3-ITD mutation significantly correlates with an increased risk of relaps...

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Bibliographic Details
Main Authors: Ly, Bui Thi Kim, Chi, Hoang Thanh, Yamagishi, Makoto, Kano, Yasuhiko, Hara, Yukihiko, Nakano, Kazumi, Sato, Yuko, Watanabe, Toshiki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688791/
https://ncbi.nlm.nih.gov/pubmed/23840454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066378
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