Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain

Rifampin has been used for the treatment of bacterial infections for many years. Clinically, rifampin has been found to possess immunomodulatory effects. However, the molecular target responsible for the immunosuppressive effects of rifampin is not known. Herein, we show that rifampin binds to myelo...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xiaohui, Grace, Peter M., Pham, Michael N., Cheng, Kui, Strand, Keith A., Smith, Christina, Li, Jing, Watkins, Linda R., Yin, Hang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2013
Schlagworte:
Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688759/
https://ncbi.nlm.nih.gov/pubmed/23568774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-222992
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