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Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain

Rifampin has been used for the treatment of bacterial infections for many years. Clinically, rifampin has been found to possess immunomodulatory effects. However, the molecular target responsible for the immunosuppressive effects of rifampin is not known. Herein, we show that rifampin binds to myelo...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Wang, Xiaohui, Grace, Peter M., Pham, Michael N., Cheng, Kui, Strand, Keith A., Smith, Christina, Li, Jing, Watkins, Linda R., Yin, Hang
التنسيق: Artigo
اللغة:Inglês
منشور في: Federation of American Societies for Experimental Biology 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688759/
https://ncbi.nlm.nih.gov/pubmed/23568774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-222992
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