Inhibition of biomaterial-induced complement activation attenuates the inflammatory host response to implantation

Although complement is a known contributor to biomaterial-induced complications, pathological implications and therapeutic options remain to be explored. Here we investigated the involvement of complement in the inflammatory response to polypropylene meshes commonly used for hernia repair. In vitro...

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Main Authors: Kourtzelis, Ioannis, Rafail, Stavros, DeAngelis, Robert A., Foukas, Periklis G., Ricklin, Daniel, Lambris, John D.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2013
Fag:
Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688753/
https://ncbi.nlm.nih.gov/pubmed/23558338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-225888
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