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15-Epi-lipoxin A(4) inhibits human neutrophil superoxide anion generation by regulating polyisoprenyl diphosphate phosphatase 1
Regulation of leukocyte activation is critical to limit unintended tissue injury during acute inflammation. On neutrophil activation, polyisoprenyl diphosphate phosphatase 1 (PDP1) rapidly converts presqualene diphosphate to presqualene monophosphate to facilitate cell activation. Lipoxins are poten...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688747/ https://ncbi.nlm.nih.gov/pubmed/23568778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223982 |
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