Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats

OBJECTIVE: There is debate as to whether fibronectin type III domain containing 5 (FNDC5) and its protein product irisin are therapeutic targets for obesity-associated maladies. Thus, we sought to examine FNDC5 mRNA within skeletal muscle of obese/diabetic-prone Otsuka Long-Evans Tokushima Fatty (OL...

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Main Authors: Roberts, Michael D., Bayless, David S., Company, Joseph M., Jenkins, Nathan T., Padilla, Jaume, Childs, Thomas E., Martin, Jeffrey S., Dalbo, Vincent J., Booth, Frank W., Rector, R. Scott, Laughlin, M. Harold
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688677/
https://ncbi.nlm.nih.gov/pubmed/23498898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2013.02.002
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