Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats

OBJECTIVE: There is debate as to whether fibronectin type III domain containing 5 (FNDC5) and its protein product irisin are therapeutic targets for obesity-associated maladies. Thus, we sought to examine FNDC5 mRNA within skeletal muscle of obese/diabetic-prone Otsuka Long-Evans Tokushima Fatty (OL...

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Autors principals: Roberts, Michael D., Bayless, David S., Company, Joseph M., Jenkins, Nathan T., Padilla, Jaume, Childs, Thomas E., Martin, Jeffrey S., Dalbo, Vincent J., Booth, Frank W., Rector, R. Scott, Laughlin, M. Harold
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688677/
https://ncbi.nlm.nih.gov/pubmed/23498898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2013.02.002
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