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GATA-3 controls T cell maintenance and proliferation downstream of TCR and cytokine signals
GATA-3 is a master regulator for T(H)2 differentiation. It is however poorly understood if GATA-3 controls mature T cell function beyond T(H)2 determination. We show that TCR signals and cytokine stimulation promoted GATA-3 expression in CD8 T cells, which controlled cell proliferation. While GATA-3...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688666/ https://ncbi.nlm.nih.gov/pubmed/23708251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2623 |
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