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Tripeptidyl Peptidase II Regulates Sperm Function by Modulating Intracellular Ca(2+) Stores via the Ryanodine Receptor

Recent studies have identified Ca(2+) stores in sperm cells; however, it is not clear whether these Ca(2+) stores are functional and how they are mobilized. Here, in vitro and in vivo, we determined that tripeptidyl peptidase II antagonists strongly activated the cAMP/PKA signaling pathway that driv...

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Detalhes bibliográficos
Main Authors: Zhou, Yuchuan, Ru, Yanfei, Wang, Chunmei, Wang, Shoulin, Zhou, Zuomin, Zhang, Yonglian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688596/
https://ncbi.nlm.nih.gov/pubmed/23818952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066634
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