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Extreme Genetic Fragility of the HIV-1 Capsid

Genetic robustness, or fragility, is defined as the ability, or lack thereof, of a biological entity to maintain function in the face of mutations. Viruses that replicate via RNA intermediates exhibit high mutation rates, and robustness should be particularly advantageous to them. The capsid (CA) do...

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Detalhes bibliográficos
Main Authors: Rihn, Suzannah J., Wilson, Sam J., Loman, Nick J., Alim, Mudathir, Bakker, Saskia E., Bhella, David, Gifford, Robert J., Rixon, Frazer J., Bieniasz, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688543/
https://ncbi.nlm.nih.gov/pubmed/23818857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003461
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