The NADPH Metabolic Network Regulates Human αB-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster

Dominant mutations in the alpha-B crystallin (CryAB) gene are responsible for a number of inherited human disorders, including cardiomyopathy, skeletal muscle myopathy, and cataracts. The cellular mechanisms of disease pathology for these disorders are not well understood. Among recent advances is t...

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Hlavní autoři: Xie, Heng B., Cammarato, Anthony, Rajasekaran, Namakkal S., Zhang, Huali, Suggs, Jennifer A., Lin, Ho-Chen, Bernstein, Sanford I., Benjamin, Ivor J., Golic, Kent G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688542/
https://ncbi.nlm.nih.gov/pubmed/23818860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003544
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