Simian Virus 40-Based Replication of Catalytically Inactive Human Immunodeficiency Virus Type 1 Integrase Mutants in Nonpermissive T Cells and Monocyte-Derived Macrophages

Integrase function is required for retroviral replication in most instances. Although certain permissive T-cell lines support human immunodeficiency virus type 1 (HIV-1) replication in the absence of functional integrase, most cell lines and primary human cells are nonpermissive for integrase mutant...

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Detalhes bibliográficos
Main Authors: Lu, Richard, Nakajima, Noriko, Hofmann, Wolfgang, Benkirane, Monsef, Teh-Jeang, Kuan, Sodroski, Joseph, Engelman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC368853/
https://ncbi.nlm.nih.gov/pubmed/14694097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.658-668.2004
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