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Expansion of a Unique Region in the Marek's Disease Virus Genome Occurs Concomitantly with Attenuation but Is Not Sufficient To Cause Attenuation

Pathogenic Marek's disease viruses (MDVs) have two head-to-tail copies of a 132-bp repeat. As MDV is serially passaged in cell culture, the virus becomes attenuated and the number of copies of the 132-bp repeat increases from 2 to often more than 20 copies. To determine the role of the repeats...

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Detalhes bibliográficos
Main Authors: Silva, R. F., Reddy, S. M., Lupiani, B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC368850/
https://ncbi.nlm.nih.gov/pubmed/14694105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.733-740.2004
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