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Increased G→A Transition Frequencies Displayed by Primer Grip Mutants of Human Immunodeficiency Virus Type 1 Reverse Transcriptase

A genetic screen based on the blue-white β-galactosidase complementation assay designed to detect G→A mutations arising during RNA-dependent DNA synthesis was used to compare the fidelity of mutant human immunodeficiency virus type 1 reverse transcriptases (RTs) with the mutations M230L and M230I wi...

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Hlavní autoři: Cases-González, Clara E., Menéndez-Arias, Luis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC368828/
https://ncbi.nlm.nih.gov/pubmed/14694133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.1012-1019.2004
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