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Peptide Inhibitors: Four of a kind beats a pair
The proapoptotic cysteine protease caspase-6 participates in the neuropathology of several diseases. Unlike the active dimeric form, the caspase-6 zymogen forms a unique tetramer that can be stabilized by allosteric inhibitors, which prevents caspase-6 activation.
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3688271/ https://ncbi.nlm.nih.gov/pubmed/22710307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1000 |
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