Impacts of Epitope Expression Kinetics and Class I Downregulation on the Antiviral Activity of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocytes

The determinants of CD8(+) cytotoxic T-lymphocyte (CTL) antiviral activity against human immunodeficiency virus type 1 (HIV-1) remain poorly defined. Although recent technological advances have markedly enhanced the ability to detect HIV-1-specific T cells, commonly used assays do not reveal their d...

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Détails bibliographiques
Auteurs principaux: Ali, Ayub, Lubong, Rachel, Ng, Hwee, Brooks, David G., Zack, Jerome A., Yang, Otto O.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC368806/
https://ncbi.nlm.nih.gov/pubmed/14694087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.561-567.2004
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