Production of Novel Ebola Virus-Like Particles from cDNAs: an Alternative to Ebola Virus Generation by Reverse Genetics

We established a plasmid-based system for generating infectious Ebola virus-like particles (VLPs), which contain an Ebola virus-like minigenome consisting of a negative-sense copy of the green fluorescent protein gene. This system produced nearly 10(3) infectious particles per ml of supernatant, equ...

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Autores principales: Watanabe, Shinji, Watanabe, Tokiko, Noda, Takeshi, Takada, Ayato, Feldmann, Heinz, Jasenosky, Luke D., Kawaoka, Yoshihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC368804/
https://ncbi.nlm.nih.gov/pubmed/14694131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.2.999-1005.2004
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