Early post-bevacizumab progression on contrast-enhanced MRI as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 Central Reader Study

BACKGROUND: RTOG 0625/ACRIN 6677 is a multicenter, randomized, phase II trial of bevacizumab with irinotecan or temozolomide in recurrent glioblastoma (GBM). This study investigated whether early posttreatment progression on FLAIR or postcontrast MRI assessed by central reading predicts overall surv...

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Main Authors: Boxerman, Jerrold L., Zhang, Zheng, Safriel, Yair, Larvie, Mykol, Snyder, Bradley S., Jain, Rajan, Chi, T. Linda, Sorensen, A. Gregory, Gilbert, Mark R., Barboriak, Daniel P.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Clinical Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688018/
https://ncbi.nlm.nih.gov/pubmed/23788270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not049
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