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Spontaneous and 5-azacytidine-induced reexpression of ornithine carbamoyl transferase in hepatoma cells.

Rat hepatoma cells that do not synthesize the hepatic enzyme ornithine carbamoyl transferase spontaneously give rise to producing cells at a low frequency. Reexpression of this differentiation trait is strongly increased by 5-azacytidine treatment, suggesting that hypermethylation plays a critical r...

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Sonraí Bibleagrafaíochta
Main Authors: Delers, A, Szpirer, J, Szpirer, C, Saggioro, D
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1984
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC368801/
https://ncbi.nlm.nih.gov/pubmed/6201723
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