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Identifying dysfunctional miRNA-mRNA regulatory modules by inverse activation, cofunction, and high interconnection of target genes: A case study of glioblastoma

BACKGROUND: Accumulating evidence demonstrates that complex diseases may arise from cooperative effects of multiple dysfunctional miRNAs. Thus, identifying abnormal functions cooperatively regulated by multiple miRNAs is useful for understanding the pathogenesis of complex diseases. METHODS: In this...

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Detalhes bibliográficos
Main Authors: Xiao, Yun, Ping, Yanyan, Fan, Huihui, Xu, Chaohan, Guan, Jinxia, Zhao, Hongying, Li, Yiqun, Lv, Yanling, Jin, Yan, Wang, Lihua, Li, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688007/
https://ncbi.nlm.nih.gov/pubmed/23516263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not018
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